THE CARBOXYLATION OF PROPIONIC ACID BY LIVER MITOCHONDRIA
نویسندگان
چکیده
منابع مشابه
The carboxylation of propionic acid by liver mitochondria.
The glycogenic effect of propionic acid (1, 2) results from the conversion of propionate carbon into carbohydrate (3, 4) and not from an indirect stimulation of carbohydrate production from other sources. The finding (5,6) that extracts of mitochondria can convert propionate and bicarbonate to an organic acid identified as succinic acid (6) provided an explanation for this glycogenic effect. Th...
متن کاملImpact of Propionic Acid on Liver Damage in Rats
Propionic acid (PA) is a short chain fatty acid, a common food preservative and metabolic end product of enteric bacteria in the gut. The present study was undertaken to investigate the effect of PA on liver injury in male rats. Male western albino rats were divided into two groups. The first group served as normal control, the second was treated with PA. The activities of serum hepatospecific ...
متن کاملPropionic acid metabolism in mouse liver slices.
Odd carbon fatty acids are considered to be oxidized in tissue by successive fl oxidation in much the same way that even carbon members of the series are (14). The terminal S-carbon unit has been investigated to some extent. Atchley (5) demonstrated propionic acid as an end-product in the oxidation of valeric acid by a rabbit enzyme system. Studies on malonate inhibition with odd carbon fatty a...
متن کاملThe uptake of silicic acid by rat liver mitochondria.
1. To gain insight into a putative role for mitochondria in silicon metabolism, mitochondrial uptake (by which it is meant the removal from the medium) of silicic acid [Si(OH)4] was studied under conditions minimizing SI(OH)4 polymerization. 2. Measurements of mitochondrial respiration and swelling indicated indirectly a significant uptake of Si(OH)4 as a weak acid, but this was not confirmed w...
متن کاملThe metabolism of itaconic acid by liver mitochondria.
The natural occurrence of a great variety of methyl and methylene-substituted dicarboxylic acids has prompted an investigation of the metabolism of some of these compounds by animal tissues. Guinea pig liver mitochondria did not catalyze measurably the oxidation of citraconate, dl-citramalate, P-methyl malate, itamalate, or paraconate. Itaconic acid’ was oxidized as rapidly as most members of t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1956
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)65752-7